Top 5 Marijuana Strains to Fight Fatigue

byRachelDugas3 minutes

While many people still assume cannabis can only be used to relax and slow down, certain strains can significantly boost energy and productivity. Most of us experience lethargy at one point or another, whether it stems from lack of sleep, illness or depression. Physical lethargy can make it hard to get out of bed and walk around throughout the day, and mental lethargy makes it difficult to concentrate on anything or to stay awake. While caffeine is probably the most popular stimulant used around the world to combat fatigue, cannabis can be just as, if not more, effective and won’t cause the comedown you may experience after the effects of your cup of coffee have worn off.

When ingesting marijuana to fight fatigue, there are a few methods that can be effective. Smoking or vaping are most useful to feel immediate effects, while tinctures or capsules will provide a longer-lasting boost of energy.

Generally, sativa strains are known for their energizing, active effects. Beyond that, the potency, flavour, and effect on the body and mind will differ depending on the synergistic balance of tetrahydrocannabinol (THC), cannabidiol (CBD), terpenes and other cannabinoids present in that strain. Here, we’ve rounded up our top five strains to fight fatigue and increase motivation.

Jack Herer


A world-renowned strain named after the cannabis activist and author, Jack Herer is an upbeat sativa strain that increases energy and creativity. While the high THC content (23%) puts this strain on the more potent side, patients describe the experience as clear-headed, focused and blissful, making it ideal for daytime motivation and productivity. Also a mood elevator, Jack Herer is effective for patients with mental or neurological disorders, anxiety, PTSD, ADHD and migraines, Jack Herer is a three-way cross of Haze hybrid, Northern Lights #5 and Shiva Skunk.

Juicy Fruit


Juicy Fruit is a flavourful hybrid that tastes like a cup of fruit punch or a pina colada. A cross of Afghani indica and pure Thai sativa with up to 20% THC, the sativa-dominant Juicy Fruit has powerful effects on both the head and body. The experience is mentally euphoric and physically relaxing yet energizing, making it ideal for patients dealing with anxiety, mood disorders, depression and physical pain.

Durban Poison


Durban Poison is a pure sativa that’s one of the most energetic and powerful strains in the world, with up to 24% THC content. The effects are strong, bringing feelings of happiness and extremely high energy. Ideal for daytime productivity, this strain is effective for patients managing depression, anxiety and chronic pain. Anxiety-prone users should be careful not to consume too much of this sativa to avoid possible paranoia. Durban Poison is also known to help reduce food cravings and promote weight loss.



Well known for its high CBD content, Harlequin offers a more mellow, balanced experience. The consistent 5:2 CBD to THC ratio makes this one of the most popular CBD strains, particularly useful for treating pain and anxiety. The effects are calming and relaxing, while helping consumers maintaining focus and alertness, thus allowing them to remain awake and productive without an overwhelming buzz.

Green Crack


If you can get past the name, you’ll find Green Crack to be useful for the boost of energy and focus it brings with it. With up to 24% THC content and a sweet, tropical flavour, Green Crack is a popular strain. A descendant of Skunk #1, this sativa strain enhances creativity and productivity, and can be used to treat fatigue, stress, ADHD, migraines and depression.